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PUBH7600 Introduction to Epidemiology

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PUBH7600 Introduction to Epidemiology

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Part 1.

Risk factors associated with tuberculosis infection among health care workers in Inner Mongolia, China. He GX et al. IJTLD 2012.

  1. What is the study design (e.g. prospective/retrospective, case-control, cohort, etc.)
  2. What is the strategy for the logistic regression models?
  3. What are the similarities and differences for each logistic regression model (Table 3)? Trends in cannabis involvement and risk of alcohol involvement in motor vehicle crash fatalities in the U.S., 2000-2018; Lira MC et al. AJPH 2021

Who are the study subjects?

  1. What are the mutually exclusive and exhaustive outcomes for the mixed effects multinomial logistic regression model? Which outcome is the control or reference outcome?
  2. What is the main predictor for these outcomes?
  3. Describe in words the results of the sub-analysis on different age strata.

Part 2.

Underage drinking, alcohol dependence, and young people starting to use prescription pain relievers extra-medically: a zero-inflated Poisson regression model. Parker MA, Anthony JC.

Exp & Clin Psychol 2019

  1. What count is being modeled?
  2. What is the primary predictor variable? What other variables are being controlled for?
  3. What is the relationship between primary predictor variable and being “non-susceptible to persistence”?
  4. What is the relationship between primary predictor variable and the rate of persistent extra-medical PPRs?

Recurrence rates after treatment of breast cancer with standard radiotherapy with or without additional radiation. Bartelink H et al. NEJM 2001

  1. There are two endpoints of interest. What are they?
  2. Which endpoint is analyzed using Cox proportional hazards?
  3. What is the model building strategy for developing the Cox proportional hazards model?
  4. What factors are associated with the endpoint?

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